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In clinical practice, ovarian cancer is frequently detected at an advanced stage, often accompanied by peritoneal dissemination or extensive intra-abdominal lesions at the time of diagnosis, complicating curative treatment

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C.DoanL.EkasumaraN.CalvinoS.ChaeF.et al (2019)

Thus, as the SLC1A5 variant is the only currently known glutamine transporter in the mitochondrial inner membrane 16 , targeting the SLC1A5 variant could be an effective strategy for selectively inhibiting glutamine metabolism in cancer cells (Fig