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Due to their chemical instability and reactivity, free radicals in excess do indiscriminate damage to cellular organelles and molecular components, including DNA, RNA, proteins, lipids, carbohydrates, and their building blocks (nucleotides, amino acids, etc.)

Without notes, a normal slowdown can look like failure

Until that qualification work is done, the imaging and fluid measures are instruments for understanding the mechanism and selecting patients, while the question of whether these drugs modify the disease still belongs to the clinical endpoints

A decade of molecular biology of retinoic acid receptors

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