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For diabetes management, less frequent dosing could result in suboptimal glycemic control, with potential increases in HbA1c levels

However, relapse rates remain high, and many currently approved medications exhibit limitations in efficacy and patient adherence

If a patient stops the medication, diabetes will relapse (if it was controlled, not cured) and weight will likely be regained, as evidenced by trials where cessation led to weight regain trends

Consulting with a benefits manager can also provide valuable insights

However, if the stone is very large and left untreated for a long while, this could result in permanent damage or kidney loss