Sarcopenia is the age-related progressive loss of muscle mass, strength, and function, according to Cleveland Clinic, which not only makes everyday activities like walking or climbing stairs more difficult but also increases the risk of falls and fractures for older adults
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As such, the association with efficacy may be the result of enhanced trafficking of the protein within the cell that ultimately modulates the cell surface abundance of the receptor, rather than the result of alterations in the receptor protein structure that may influence ligand affinity
The immunocomplex was detected by enhanced chemiluminescence detection (ECL, GE HealthcareUK, Buckinghamshire, UK)