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Importantly, either approachusing an MAO-B inhibitor or an allosteric Cav1 channel modulator to decrease mitochondrial stress in axons and somasis sufficient to prevent SNc dopaminergic neuron degeneration [37]

Deficiency in vitamin B12 can worsen anemia in thalassemia patients

NNMT, nicotinamide N-methyltransferase, is found throughout the body but is particularly active in fat tissue

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This is a protocol that normally produces robust tolerance