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Several patterns appear consistently: Loss of lean muscle mass Inadequate protein intake Nutrient deficiencies, particularly vitamin D and magnesium This matters because muscle mass plays a direct role in supporting skeletal health

Progress in Retinal and Eye Research, 2003

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Ongoing research continues to evaluate the broader role of this peptide in complex cellular environments, including its potential interactions with receptor-mediated pathways, extracellular signaling systems, and coordinated biological responses under controlled laboratory conditions