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Magnesium: Required for the synthesis of glutathione within the cell

Kumar A, Sharma A, Chen Y, Jones MM, Vanyo ST, Li C, Visser MB, Mahajan SD, Sharma RK, Swihart MT

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Here, we show that hepsin deficiency in mice exacerbates acetaminophen toxicity compared to wild-type mice, leading to more severe liver pathology, elevated oxidative stress, and greater mortality within 6 h after exposure