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Although the primary endpoint here is the treatment of liver damage, one of the trials secondary endpoints is alcohol consumption

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However, these symptoms can also result from the caloric deficit associated with significant weight loss, adjustment to dietary changes, or pre-existing hormonal imbalances that become more apparent during metabolic transition

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1 Although oral and perioral pigmentation may be physiologic in nature, particularly in individuals with a darker complexion, throughout the course of disease it is possible for the oral mucosa and perioral tissues to assume a variety of discolorations, including brown, blue, gray, and black