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J Androl 2012;33(2):170-175
At present, increasing evidence has shown that compounds derived from natural medicines exert a variety of beneficial effects, including antioxidant, anti-inflammatory, and anti-apoptosis effects [119,120,121]
In terms of ubiquitination, the small molecule N6F11 specifically recruits the E3 ligase TRIM25, which catalyzes the polyubiquitination of lysine 48 (K48) on GPX4, leading to its proteasomal degradation
Antioxid Redox Signal 15:15831606 Ray PD, Huang B-W, Tsuji Y (2012) Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
Reconstitution math
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