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Indeed, it has been suggested that systematic abnormalities in ASD, such as mitochondrial dysfunction, may arise from environmental triggers 14 in genetically sensitive subpopulations

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Tirzepatide Versus Insulin Glargine In the open-label SURPASS-4 study, patients at increased cardiovascular risk on one to three oral glucose-lowering medications ( metformin sulfonylurea SGLT2 inhibitor) were randomised to once weekly tirzepatide 5, 10 or 15 mg or once daily insulin glargine (titrated following a treat-to-target algorithm) for up to 104 weeks with the primary timepoint at 52 weeks