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A 4 mg maintenance dose is also being studied alongside 9 mg and 12 mg

Week 1 to 2: Most patients notice the sleep change first

To quantify apoptotic cells in the heart, one-step TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) in situ apoptosis assay was performed according to the manufacturers instructions (eLabscience, Elab Fluor 647, # E-CK-A324)

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