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Initial concerns regarding the possible link between the use of GLP-1 RAs and the development of pancreatitis or pancreatic cancer have not been supported by the results of RCTs [53,54], or real-world data [29,55,56]
In particular, the risk of hypoglycaemia increases when Saxenda is combined with insulin or sulfonylureas, and dose reductions of these medications may be necessary
Reports of depression, anxiety, and suicidal ideation have attracted significant regulatory and media attention
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