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A recent study found that gut bacterial metabolite, Ruminococcaceae isoamylamine (IAA), which is enriched in older adults and aged mice, promotes age-related cognitive dysfunction by promoting microglial cell death (Teng et al., 2022)

Glutathione neutralizes the free radicals that drive that process, which is why it is a core part of how we support chronic inflammation at the cellular level

Asadi-Pooya et al., 2023)

But glutathione is on the NPRA FoodDrug Interphase (FDI) Negative List , meaning it cannot be used in food formats

Given tirzepatide's demonstrated efficacywith weight loss exceeding that achieved with other approved medications there is no evidence of additional benefit from adding lipotropic injections , and this combination is not endorsed by clinical guidelines