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FOXO4-DRI has three main pharmacogenetic advantages: its stability (resistance to degradation by cellular proteases), half-life (compared to L-peptide equivalents, it's longer), and cell-penetrating properties (cell-penetrating sequences improve intracellular delivery)
Verratti, V
This result was not attributable to publication bias, or a significant between-studies heterogeneity
That said, the compound has not been through full Phase III trials or FDA drug approval
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