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Other mechanisms such as VPA-induced lipid peroxidation and glutathione depletion could also contribute to hepatotoxicity [59]

For semaglutide specifically, the benefits for sleep apnea stem primarily from: Reduced airway obstruction : By decreasing fat deposits around the neck and throat, semaglutide widens the airway, reducing the likelihood of collapse during sleep Improved lung function : Weight loss reduces pressure on the chest and diaphragm, making breathing easier Decreased inflammation : Obesity-related inflammation can worsen OSA

[2] [3] Clinical trial data from the SURPASS program and SURMOUNT studies provide robust evidence regarding tirzepatide's effects on gastric emptying and digestive function

Res 196 , 3141 (2018)