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Research has shown that certain bitter compounds in plants, such as ginseng and gentiana scabra, can stimulate GLP-1 secretion, suggesting their possible use as natural GLP-1 agonists

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The infection becomes sepsis when that response becomes excessive, harmful, disbalanced and leads to systemic inflammation, probably due to immunosuppression (5)

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Among these, CBP-mediated -hydroxybutyrylation can inhibit p53 acetylation, thereby suppressing p53 activity and promoting tumor progression (Fig

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