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In vivo , the four-week-old male mice were injected intraperitoneally with 100 l of virus containing 5 10 ^ 11 AAV8-shLRP1-GFP and AAV8-scramble (scr)-GFP and then treated with CCl 4 (0.6 l /g body weight, three times a week) for another 4 weeks to establish fibrosis model
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