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Although oral Semaglutide offers a non-injectable dosing option, it faces a number of challenges, notably bioavailability, metabolic stability, and gastrointestinal side effects (Ke et al., 2024) (Table 2)

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Ohara M, Ogawa K, Suda G, Kimura M, Maehara O, Shimazaki T, Suzuki K, Nakamura A, Umemura M, Izumi T, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ohnishi S, Sakamoto N