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According to our study, NAC could serve as an efficacious agent for suppressing ferroptosis-induced cytokine secretion
16 This change is supported by findings from the 2024 STEP-HFpEF DM trial
The supplement industry can help by declaring research chemicals are not dietary supplements to make it clear to consumers that supplements and research chemicals are not the same thing
While regulation of iron metabolism-related proteins or the use of iron chelators can reduce intracellular labile Fe 2+ levels and inhibit ferroptosis, current chelators lack tissue and cellular specificity and may interfere with neurophysiological functions, thereby limiting their clinical applicability
Liraglutide treatment in 5xFAD mice improved spatial memory, an effect associated with enhanced aerobic glycolysis in astrocytes which improved cell support, promoting neuronal survival [51]
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