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TB-500 (synthetic TB4) has been clinically tested for its wound healing potential, with the following two studies worth noting: In a randomized, double-blind, placebo-controlled study with dose escalation, patients suffering from venous stasis ulcers were administered synthetic TB4 locally over a period of 84 days

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Specific oligonucleotide primers for 3-AR and actin were used, generating PCR products of 234 base pairs and 559 base pairs, respectively

You wont see dramatic changes overnight, but with consistent use, the improvements in firmness and texture can be noticeable and long-lasting