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These differences matter because access challenges, such as refill difficulty and medication switching, show up across every care pathway, suggesting that no single model has solved the problem of continuity

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Phase 2 trial data (Jastreboff et al., NEJM, 2023) showed mean body weight reductions of approximately 24% at 48 weeks with the highest dose, with no clear plateau observed

3e) or erastin (Fig

Insurance coverage often comes with strict requirements, like a BMI of 30 or higher, a diagnosis of type 2 diabetes, or a BMI of at least 27 with additional risk factors