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Endocrine Society Clinical Practice Guideline

The published TRIUMPH-1 and TRIUMPH-4 data suggest discontinuation rates due to adverse events climb with dose, and that the 12 mg arm of retatrutide has shown the highest discontinuation figures of the three compounds at their respective top doses in published Phase 3 trials [2][10]

Bone health is affected alongside muscle loss, especially among older GLP-1 users

Regular check-ins with your healthcare provider help determine the appropriate duration for your specific situation and monitor for any ongoing retatrutide side effects

Novo Nordisks Saxenda (liraglutide) was the first GLP-1 analog to treat obesity