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The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

Eli Lilly also seems more proactive about getting its marquee drug to priced-out patients

Self-administered therapy without oversight means no one is tracking outcomes, adjusting dosing, or managing side effects

These may be mild and temporary, but they can also interfere with hydration, nutrition, work, exercise, or daily comfort

These results, while promising, require confirmation in the ongoing Phase 3 programme before any conclusions about comparative efficacy can be drawn