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Emphasis should be placed on clarifying the regulatory pathways of immune-metabolic axes mediated by dual-regulating molecules through hub molecules such as mTOR and HIF-1, and expanding mechanistic exploration in emerging fields such as the gut-lung axis and neuro-immune-metabolic crosstalk (Lv et al., 2024)
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CBT addresses this by helping patients develop adaptive coping mechanisms, thereby reducing avoidance, alleviating fatigue, and enhancing social engagement [160]
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