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Characterization of clinical manifestations in the co-occurring phenotype of attention deficit/hyperactivity disorder and autism spectrum disorder
High: Too much pressure may be asymptomatic at first, but high blood pressure can contribute to serious health problems, such as stroke, heart disease, and kidney disease
Mice exposed to chronic unpredictable mild stress (CUMS) for 6 weeks showed increased hypothalamic corticotropin-releasing hormone concentrations, elevated corticosterone levels and increased blood ammonia, which corresponded with anxiety-like behaviors, demonstrating HPA axis involvement in anxiety pathogenesis (Jia et al., 2024)
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