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The resulting graph shows an early distribution phase followed by the slower elimination phase
Elevated homocysteine levels are associated with increased risk of heart attack, stroke or dementia
When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects
It is a synthetic form of B12 with cyanide attached to the cobalamin (the B12)
10.1016/j.toxicon.2018.04.029 63 DuchG.SandersonJ
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