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A complicating factor in clinical trials has been the significant inter-individual variability in susceptibility to APAP toxicity 14

No significant inhibitory effects on ScGrx7 catalysis were observed at inhibitor concentrations of up to 1.5 mM

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Host interactions have been shown to induce persister formation in numerous pathogens, with the production of reactive oxygen and nitrogen species heavily implicated in the collapse of bacterial metabolic activity and entry into an antibiotic-tolerant state

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