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European Journal of Pharmacology , vol

Yderstraede KB et al

They are designed to support the body's natural GLP-1 activity rather than replicate prescription medications (7)

Its just much harder for them to be competitive in the new era of small-molecule GLP-1 receptor agonists, oral peptide therapeutics. Secher added that there may be a physiological limit to the amount of GLP-1 that can be produced with endogenous inducers of endogenous GLP-1 release compared with pharmacological inducers