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Laboratory studies examine receptor activation, cyclic adenosine monophosphate (cAMP) signaling, kinase activation, intracellular trafficking, second messenger communication, transcriptional regulation, peptide metabolism, and molecular adaptation following peptide-receptor interaction
Extracellular adenosine can be transported into cells as a function of a concentration gradient where it is phosphorylated to AMP by adenosine kinase or degraded to inosine by ADA
5F) [19]
The FAK-paxillin pathway activation enhances fibroblast migration to damaged areas
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