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In addition, enhanced plasma levels of pyroptosis markers were detected in COVID-19 patients, and the levels of caspase -1 and IL-18 in serum correlated with the degree of COVID-19 severity (220, 221), particularly in elderly patients (234)

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Genetic Variations in Antioxidant Enzymes: The Individual Risk Factor Not everyone with hemochromatosis develops cancer, and genetics may explain why

Intervention studies highlight therapeutic potential: Lactobacillus johnsonii supplementation reduces immune cell activation in lungs and Th2 cytokine expression (IL-4, IL-5, IL-13, IL-17), suggesting microbiota-targeted strategies for AHR modulation (Aagaard et al., 2012)