Nrf2 is involved in not only the regulation of GSH synthesis and reduction via upgrading some enzymes and proteins (SLC7A11, GCLM, GCLC, GR) but also the activation of GSH-dependent antioxidant enzymes (GPX, GST) [200, 201]
Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men short version
In the article, the many functions of glutathione are described as follows: Clinically, glutathione is thought to critical for the following disease and body processes References Mechanism of Action 1-4 Glutathione has many mechanisms in the body to support its role as an antioxidant, a detoxifier, and its involvement in many enzymatic processes including redox reactions
It is involved in various cellular processes, including DNA synthesis and repair, amino acid transport, and detoxification of harmful substances
Reactive oxygen and nitrogen species (Ros/rns) scavenging assays, oxidative stress biomarkers, and chromatographic/chemometric assays