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Alpha-myosin heavy chain lactylation maintained sarcomeric structure and mitigated heart failure development (32), whereas lactate-regulated histone lactylation was implicated in pathological hypertrophy (33)
GIP receptor activation complements GLP-1 effects by enhancing insulin sensitivity and potentially improving fat metabolism
Oral Administration of Cinchonine Improved Liver Injury of Ob/Ob-GAN NASH Mice As shown in Figure 6, the GAN diet led to a significant increase in serum ALT, AST, ALP, and LDH levels in ob/ob mice
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PMID: 62 SilvagniEBortoluzziACiancioGGovoniM
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