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It is important to be cautious and seek medical advice when necessary to ensure the safety of using these substances together, especially for individuals who regularly consume alcohol or those with pre-existing liver conditions

Immediate medical attention is required

Because it competes at the nicotinamide substrate site rather than the SAM cofactor site, it is also used as the substrate-competitive reference compound against which bisubstrate and covalent NNMT inhibitors are benchmarked

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