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The SURMOUNT-1 trial (Jastreboff et al., New England Journal of Medicine 2022) enrolled 2,539 adults with obesity and demonstrated 15% to 20.9% total body weight loss over 72 weeks
22 There was amelioration of glucose and lipid metabolism and improved cell mass in obese diabetic (db/db) mice with dual agonist use
On the day of patent expiry, generic manufacturers launched lower-priced versions
With the compounding era largely over, the safe path is an FDA-approved medication prescribed and supervised by a licensed provider
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