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GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide were studied in STEP (semaglutide, weight management, NEJM 2021), SURMOUNT (tirzepatide, weight management, NEJM 2022), and SURMOUNT-OSA (tirzepatide, obstructive sleep apnea, NEJM 2024)
Interestingly the ABC transporters are often upregulated in chemoresistant cancers, since they efficiently excrete chemotherapeutic drugs such as doxorubicin, taxane- and platinum-based drugs from cancer cells
Stop using semaglutide and contact your healthcare provider immediately if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting
Simultaneous epitope and transcriptome measurement in single cells
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