In late August 2015, the US FDA issued a warning that drugs like sitagliptin, saxagliptin, linagliptin, alogliptin, and other DPP-4 inhibitors could cause joint pain that can be severe and disabling
Common side effects include nausea, diarrhea, vomiting, decreased appetite, and constipation
Its not included with the drug information and patients are using Ozempic unaware of the risk they face
Vascular calcification mechanisms: updates and renewed insight into signaling pathways involved in high phosphate-mediated vascular smooth muscle cell calcification
Additionally, GLP-1 appears to promote neurogenesis and enhance synaptic plasticity in the hippocampus, a brain region critical for memory formation that is particularly vulnerable in Alzheimer's disease