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In rodent studies, glycyrrhizin administration reduces reactive oxygen species (ROS) levels in liver mitochondria, indicating mitigation of mitochondrial oxidative stress ( 4 induced fibrosis models reveals that glycyrrhizin upregulates multiple members of the glutathione S-transferases family (Gstm1, Gstm2, Gsta1), which participate in glutathione metabolism and xenobiotic detoxification ( 3.3 Regulation of hepatocyte apoptosis In liver injury, apoptosis is a major mode of hepatocyte death
Discussion Although glutathione is quite popular, its efficacy as a skin-lightening agent has yet to be properly evaluated
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor
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Harvey CJ, Thimmulappa RK, Sethi S, Kong X, Yarmus L, Brown RH, et al
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