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However, clinical rigor dictates vigilance: the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency has flagged a possible rare risk of non-arteritic anterior ischemic optic neuropathy, a form of sudden blindness, associated with the use of these drugs

Ozempic itself does not destroy muscle, but the caloric deficit it creates can lead to lean mass reduction if resistance training and adequate protein intake are not maintained

"Some experience this at starting doses," she notes, adding that she has many patients who have lost significant weight without ever escalating the dose

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