glp-1 options for type 2 diabetes and obesity 2025 agonists changes in body mass and composition in adults with overweight or with or without mellitus: a systematic review and meta-analysis GLP-1 Trends

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Overall, current evidence supports a model in which gut dysbiosis may promote early intestinal -synuclein pathology, followed by gut-to-brain propagation and chronic neuroinflammation, and ultimately to progressive dopaminergic neurodegeneration

The main omega-3s present in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which impact brain development and function ( Fish oil is an excellent source of these fatty acids

Short-acting and prolonged-acting GLP-1 receptor agonists (GLP-1RAs) have been developed

The reviewer JD declared a shared affiliation with the authors MM, ZG, SZ, EI to the handling editor at the time of review