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Sirtuin Activation: NAD+ activates sirtuins, proteins that regulate cellular health, inflammation, and longevity

183 The recruitment of these proteins leads to the formation of the death-inducing signaling complex, which induces the internalization of the receptor, and apoptotic reactions ensure via either caspase- or mitochondrial-mediated cascades

doi:10.1371/journal.pone.0033066

These proteins, in turn, may induce apoptosis of old cells, thereby reducing the old cell burden in tissues

Sirve como reactivo analtico de alta pureza en procesos de purificacin de protenas, especficamente en el sistema de marcado con GST