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Uric acid serves as a major plasma antioxidant, scavenging 1 O and OH [121]

Reduction of MTT by glutathione S-transferase

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Nevertheless, since GSH cannot be administered directlybecause of its insufficient absorption, stability and solubilityanalogues have been obtained, through modifications at the -glutamyl, cysteine and glycine moieties, and/or the functionalisation of the central cysteine, that are able to inhibit the activity of GSTs 69,87,105