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FOXO4-DRI enhances tissue rejuvenation By clearing out senescent cells, FOXO4-DRI can cause a significant increase in the regeneration of tissues and may restore their functionality, making it a promising agent for reversing cellular aging effects (4)
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S2CID 22194443
Very recently, direct-immunofluorescence microscopy of rat lower hindlimb muscles revealed that with aging, extracellular matrix (ECM)-bound HGF undergoes tyrosine residue (Y) nitration, as visualized by anti-nitrated Y-HGF monoclonal antibodies (mAbs, rat clones 3A11C6 and 6B82C3 raised in-house) in experiments employing three age-groups of young (2-month-old), adult (10-month-old), and old rats (20-month-old) 32