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Traditionally, the EECs were classified by the peptide they secrete, although more recently, application of RNA sequencing has led us to know that a single EEC can produce multiple hormones within an individual, and different hormonal promoters may be active at different times (90, 91) The distribution of the different EECs across the gastrointestinal tract that is generally accepted is: Stomach: P/D1 cells (ghrelin), D cells (somatostatin), G cells (gastrin), and ECL cells (histamine)
The Sustained Release (SR) technology of Metformin ensures gradual drug release, providing prolonged glucose control with reduced gastrointestinal side effects compared to immediate-release formulations
Osinski C, Le Glau L, Poitou C, de Toro-Martin J, Genser L, Fradet M, et al
Prescriptions are issued only when clinically appropriate and are always at the discretion of your licensed clinician
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