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But in general, turning a peptide (including GLP-1 or insulin) into an oral formulation means overcoming three major challenges: protecting the peptide from digestion in the stomach, improving absorption of the peptide via the gut, and slowing down the enzymatic breakdown and excretion of the peptide once it is in the blood

Combining the medication with healthy eating and regular physical activity maximizes results

Alternative diabetes or weight management therapies should be considered in consultation with specialist services

Eligible participants were adults aged 18 and older without diabetes