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Mostafa ME et al
Copyright by Elsevier BV, Inc
People with diabetes who were taking semaglutide were 45% less likely to be diagnosed with depression, and 44% less likely to have anxiety
However, evidence remains limited and neither is recommended as first-line treatment in UK guidance
In pre-clinical models, BPC 157 has been observed to: Upregulate vascular endothelial growth factor (VEGF) , promoting new blood vessel formation in damaged tissue Modulate nitric oxide (NO) synthesis pathways, influencing vascular tone and healing cascades Interact with the growth hormone receptor system , potentially amplifying downstream tissue repair signaling Demonstrate cytoprotective effects along the gastrointestinal tract its native home territory as a gastric peptide Exhibit apparent neuroprotective properties in rodent models of CNS injury BPC 157 stability in gastric acid unusual for peptides has made it a focus of GI mucosal repair research
