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The stained cells were then examined using a Zeiss AxioCam, CCD camera attached to the Zeiss Axiovert 200 M inverted microscope with fluorescence/phase or DIC imaging (Carl Zeiss Light Microscopy GmbH, Gottingen, Germany) and processed with MetaMorph Software (Molecular Devices Inc., Sunnyvale, CA)

As both type 1 and 2 diabetes are associated with reduction of functional cells, this effect is desirable in diabetes treatment

There are older generic medications like phentermine or topiramate that are sometimes used for weight loss or other newer branded medications that are FDA-approved for weight loss

Notably, cotadutide also alleviated fibrosis to a greater extent than liraglutide or obeticholic acid, despite dose adjustment to achieve similar weight loss in two preclinical mouse models of NASH