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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) emerged as a promising class of drugs and have been shown to be effective as a key regulator in managing glucose metabolism-associated diseases such as type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), cardiovascular effects, nephrological complications, diabetes, non-alcoholic fatty liver (NAFLD), as well as to control obesity

The steroids his doctor prescribed to treat his breathing condition made him gain weight, which only made exercise more challenging

The process as claimed in claim 1, wherein PGi represents a protecting group selected from alkyloxy carbonyl such as methoxy carbonyl, ethoxy carbonyl, tert.butoxycarbonyl (Boc)

Based on patterns observed in clinical trials and the known pharmacology of the drug class, monitoring would likely need to be most intensive during the dose-escalation phase, when haemodynamic effects are most pronounced

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