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According to a study in 2017, cells of the hippocampus, responsible for learning and memory, are more at risk of oxidative stress than other areas
Genistein administration induced Nrf2 enhancement by activation/phosphorylation of keap1, sirt1, MAPK-ERK1/2, PKC, and estrogen receptor in other cells or tissues, such as: hippocampal tissue, hypothalamic paraventricular nucleus, ovary, and Caco-2 cells [131, 135,136,137]
(2011a)
Currently, there is no confirmed evidence of side effects
This is an evidence for the relationship between high IgE level and the oxidative stress occurrence
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