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The two BPC-157 forms covered by the recommendation The committee question covered two related bulk drug substances: BPC-157 free base and BPC-157 acetate
The pipeline continues to expand: Novo Nordisk filed an NDA for CagriSema (semaglutide + cagrilintide) in December 2025, which achieved 22.7% weight loss in the REDEFINE 1 trial, and Eli Lilly reported Phase 3 results for retatrutide , a triple GIP/GLP-1/glucagon agonist that delivered 28.7% weight loss
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Injection site reactions appear in pain and swelling at the injection site
Recent postmarketing data (reports from people whove used the medication since it became available for use) has also identified more serious complications , including ileus (a type of intestinal blockage) and severe constipation leading to fecal impaction
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