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However, the bulk degradation of PLGA may cause localized inflammation due to acidic products formed, especially in poorly buffered systems 97
This allows oral megadoses (e.g., 1,000 g or more daily) to raise serum B levels even in individuals with pernicious anemia or low stomach acid
In animal models, it has been studied for its potential to protect the stomach lining from damage caused by toxins or NSAIDs and to help manage conditions like inflammatory bowel disease (IBD)
Follow-up labs every few months confirm the protocol is working as intended
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